0731-88458227

王炜

2022年11月28日 20:43  点击:[]


王炜



职称/职位

   教授,博导;药学院党委副书记院长


课程教学

   《天然药物化学》,《药学英语》,《博士英语》等


研究方向

   研究领域:天然药物化学、中药化学

   研究兴趣:

   1.中药、天然药物活性物质的发现、活性分析研究

   2. 高通量筛选新方法的建立及靶向增效研究


荣誉和奖励

   1. 教育部长江学者特聘教授,

   2. 国家百千万人才工程“有突出贡献中青年专家”,

   3. 湖南省芙蓉学者特聘教授

   4. 湖南省“工人先锋号”(集体)

   5. 湖南省“最美丝路青年”(集体)

   6. 2022:湖南省中医药科技奖一等奖

   7. 2021:中华中医药学会科学技术奖三等奖

   8. 2017: 四川省科技进步奖三等奖

   9. 2005:湖南省科技进步二等奖


科研项目

  1.  国家自然科学基金(82174078,2022/01-2025/12,主持)

  2.  国家科技部国家重点研发计划(2018YFC1707902,2018/01-2023/12主持)

  3.  国家科技部科技基础资源调查专项(2018FY100703,2018/01-2023/12主持)

  4.  国家自然科学基金(81874369,2019/1-2022/12,主持)

  5.  国家自然科学基金(81673579,2017/01-2020/12,主持)

  6.  国家自然科学基金(81374062,2013/01-2017/12,主持)

  7.  湖南省重点研发计划项目(2018SK2110,2018/07-2021/06,主持)

  8.  国家中医药管理局国际合作专项(GZYYGJ2017016,2017/07-2018/07,主持)

  9.  国家中医药管理局(ZYBZH-Y-HUN-23,2016/7-2018/12,主持)

  10.  十二五国家863计划海洋技术领域主题项目(SS2013AA09002,2012/10-2017/10)

  11.  美国农业部国际合作USDA (6408-41000-008-13N, 2012/5-2017/4,中方主持)


代表论文

  1. Biomimetic Hybrid Membrane-Coated Xuetongsu Assisted with Laser Irradiation for Efficient Rheumatoid Arthritis Therapy. Huanghe Yu, Jialong Fan, Nuzhat Shehla, Yixing Qiu, Ye Lin, Zhou Wang,  Liang Cao, Bin Li,Muhammad Daniyal, Yan Qin, Caiyun Peng, Xiong Cai,* Bin Liu,* and Wei Wang*. ACS NANO. IF:15.881

  2. Chunyi Tong, Xianghua Zhong, Yuejun Yang, Xu Liu, Guowei Zhong, Chang Xiao, Bin Liu*,Wei Wang*, Xiaoping Yang. PB@PDA@Ag nanosystem for synergistically eradicating MRSA and accelerating diabetic wound healing assisted with laser irradiation. Biomaterials. 2020, 243,119936.IF:12.479

  3. Jing Ning#,Wei Wang#, Guangbo Ge#, Peng Chu, Feida Long, Yongliang Yang,* Yulin Peng, Lei Feng,* Xiaochi Ma*, and Tony D. James. Targeted Enzyme Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy. Angewandte Chemie-International Edition. 2019.IF: 15.336

  4. Bin Liu, Wenmiao Wang, Jialong Fan, Ying Long, Feng Xiao, Muhammad Daniyal,Chunyi Tong, Qian Xie, Yuqing Jian, Bin Li, Xiaochi Ma*,Wei Wang*. RBC membrane camouflaged prussian blue nanoparticles for gamabutolin loading and combined chemo/photothermal therapy of breast cancer. Biomaterials. 2019, 217, 119301. IF: 12.479

  5. Mahwish Siddiquia, Atia-tul-Wahabb*, Almas Jabeen, Yan Wang,Wei Wang, Atta-ur-Rahman, M. Iqbal Choudhary*, Whole-cell fungal-mediated structural transformation of anabolic drug metenolone acetate into potent anti-inflammatory metabolites. Journal of Advanced Research. 2020, 24, 69–78.    IF: 10.479

  6. Jing Ning#, Tao Liu#, Peipei Dong#,Wei Wang, Guangbo Ge, Bo Wang, Zhenlong Yu, Lei Shi, Xiangge Tian, Xiaokui Huo, Lei Feng*, Chao Wang, Chengpeng Sun, Jing-Nan Cui, Tony D. James, and Xiaochi Ma*.Molecular design strategy to construct the near-infrared fluorescent probe for selectively sensing human cytochrome P450 2J2. Journal of The American Chemical Society, 2019, 141(2), 1126-1134.  IF: 15.419  中科院一区

  7. Zhenlong Yu#, Xiangge Tian#, Yuling Peng#, Zheng Sun, Chao Wang, Ning Tang, Bin Li, Yuqing Jian,Wei Wang*, Xiaokui Huo and Xiaochi Ma*,Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells. Journal of Pineal Research, 2018;65:e12478.   IF: 13.007  中科院一区

  8. Chunyi Tong#, Xizhi Zhang#, Jialong Fan, Bin Li, Bin Liu*, Daniyal Muhammad,Wei Wang*. PEGylated mBPEI-rGO nanocomposites facilitate hepotocarcinoma treatment combining photothermal therapy and chemotherapy. Science Bulletin, 2018.  IF: 11.780  中科院一区

  9. Chang Xiao, Chunyi Tong, Jialong Fan, Zhou Wang, Qian Xie , Ying Long , Peidong You ,Wei Wang**, Bin Liu*. Biomimetic nanoparticles loading with gamabutolin-indomethacin for chemo/photothermal therapy of cervical cancer and anti-inflammation. Journal of Controlled Release339 (2021) 259–273.  IF:9.776  中科院一区

  10. Yan Qin, Caiyun Peng, Wei Yang, Jialong Fan, Wen-Bing Sheng, Pan Yi, Yixing Qiu, Huanghe Yu, Sai Jiang,Wei Wang*, Bin Liu*. A bi-functional fluorescent probe for visualized and rapid natural drug screening via GSTs activity monitoring.Sensors and Actuators: B. Chemical.2021, 328, 129047.    IF: 7.460  中科院一区

  11. Hongyan Zhou, Ruxin Luo, Qian Xie, Peidong You, Huanghe Yu, Yan Qin, Chunyi Tong, Muhammad Danial, Bin Liu*,Wei Wang*. A new fluorescence method for monitoring PNK activity in vitro, natural compounds screening and intracellular imaging, Sensors and Actuators B: Chemical, 2020, 129203.   IF: 7.460   中科院一区

  12. Jialong Fan#, Bin Liu#, Ying Long, Zhou Wang, Chunyi Tong,Wei Wang*, Peidong You, Xuanming Liu*. Sequentially-targeted biomimetic nano drug system for triple-negative breast cancer ablation and lung metastasis inhibition. ActaBiomaterialia. 2020.   IF: 8.947   中科院一区

  13. Yan Qin, Jialong Fan, Wei Yang, Bingbing Shen, Yupei Yang, Qi Zhou, Wenming Chen, Muhammad Daniyal, Feng Xiao, Wen-Bing Sheng, Huanghe Yu, Jiantao Zhou,Wei Wang*, Chunyi Tong, Bin Liu*. An endogenous Cys-assisted GSH@AgNCs-rGO nanoprobe for real-time monitoring of dynamic change in GSH levels regulated by natural drug. Analytial Chemistry, 2020,92, 2, 1988-1996.   IF: 6.986  中科院一区

  14. Ruxin Luo,Hongyan Zhou,Wenya Dang,Ying Long,Chunyi Tong,QianXie,Muhammad Daniyal,Bin Liu*,Wei Wang*. A DNAzyme-rGO coupled fluorescence assay for T4PNK activity in vitro and intracellular imaging. Sensors and Actuators B: Chemical. 2020.  IF: 7.460   中科院一区

  15. Yan Qin, Muhammad danial, Wenmiao Wang,Yuqing Jian,Wei Yang, Yixing Qiu, Chunyi Tong, Wei Wang*, Bin Liu*, An Enhanced Silver Nanocluster System for Cytochrome c Detection and Natural Drug Screening targeted for Cytochrome c. Sensors and Actuators B-Chemical. 291(2019)485–492.   IF: 7.460   中科院一区

  16.  Lei Feng#, Yongliang Yang#, Xiaokui Huo#, Xiangge Tian#, Yujie Feng, Hanwen Yuan, Lijian Zhao, Chao Wang*, Peng Chu, Feida Long, Wei Wang*, and Xiaochi Ma*,Highly selective NIR probe for intestinal β-Glucuronidase and High-throughput screening inhibitors to therapy intestinal damage. ACS Sensors, 2018,3, 1727−1734.   IF: 7.711  中科院一区

  17. Chunyi Tong#, Chuan Zhao#, Bin Liu*, Bin Li, Zhaoyang Ai, Jialong Fan, and Wei Wang*, Sensitive Detection of RNase A Activity and Collaborative Drug Screening Based on rGO and Fluorescence Probe. Analytical Chemistry, 2018, 90 (40), 2655-2661.  IF:6.986   中科院一区


联系方式

  电话:0731-88458305

  传真:

  邮箱:wangwei402@hotmail.com


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